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Nature
@nature · 昨天

降脂新药临床试验折戟,科学家重新审视Lp(a)靶向疗法前景

曾被视为心血管领域突破的降脂蛋白(a)药物在一项关键试验中未显示获益,科研界正评估这一结果对后续研发的影响。

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盘口解读AI 估计 · 非真实赔率
为什么是 22%

近期一项关键试验失败,同类III期读出多集中在2026-2027年且不确定性高,短期出现明确阳性结果概率偏低。

怎么算赢

以药企官方公告或同行评议期刊/权威会议公布的III期主要终点结果为准,需明确达到主要心血管终点。

题材 · 截止

热点 · 结算 2027-02-03

概率走势
22%27%32%当前 22%

Cassandra Willyard is a science journalist in Madison, Wisconsin.

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Bluesky Facebook LinkedIn Reddit Whatsapp X Save article View saved research Lipoprotein(a) is a cholesterol-carrying molecule that raises the risk of cardiovascular disease. Credit: Juan Gaertner/Science Photo Library

In early September, pharmaceutical giant Novartis issued a press release that sent shock waves through the cardiology community. A drug called pelacarsen, once expected to be a potential blockbuster, had failed to reduce the risk of heart problems and stroke in people with underlying cardiovascular disease.

More muscle, less belly fat: mutations to a gene are linked to wide-ranging benefits

评论 · 3
C
Caleb30分钟前

我没那么确定,现在市场波动太大了。

L
Liam2小时前

盘口已经反应得差不多了,进场性价比不高。

S
Sofia3小时前

新闻里第 3 点才是关键,市场好像还没充分定价。

评论与发帖将在 M2 接入真实账户后开放